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Category:2010s Bengali-language films
Category:2020s Bengali-language films
Category:Indian comedy films
Category:Indian drama films
Category:Bengali remakes of Hindi films
Category:Films directed by Bappaditya BandyopadhyaySeparation of codominant alleles at allelic polymorphisms.
The locus for hereditary breast cancer in human females, BRCA1, was examined for markers with allelic polymorphisms. Of 14 polymorphic markers, 4 were tested for segregation using a panel of female relatives, and seven were also studied in pedigrees from one of the founder populations of Newfoundland and western Canada. The markers included intragenic and flanking RFLPs, VNTRs, and microsatellite polymorphisms. While one marker, the intron 7 RFLP, could not be typed reliably, the other three markers (a (CA)n repeat, a microsatellite polymorphism, and a (T/G)n microsatellite polymorphism) were demonstrated to be codominant. Two alleles that differed in length at the microsatellite (T/G)n polymorphism were found to be in linkage disequilibrium. The alleles at this microsatellite could be differentiated by PCR-based genotyping. The BRCA1 alleles were found to segregate in a dominant pattern in families with a BRCA1 mutation and a BRCA1 polymorphism. The pattern of inheritance of the RFLP (CA)n polymorphism was consistent with both a codominant and a dominant effect. Further, the microsatellite (T/G)n polymorphism segregated in a codominant fashion with both the presence and the absence of the BRCA1 mutation in a sample of families from Western Canada. The results demonstrate that codominant alleles can be used as genetic markers, and this approach should be useful in large studies of genealogical pedigrees.Hilford, Queensland
Hilford is a rural locality in the Shire of Burdekin, Queensland, Australia. In the, Hilford had a population of 3 be359ba680
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